Serious infection- Neonate < 1 wk and < 2 kg: 75 mg/kg IM, IV q 12 h. Neonate < wk and > 2 kg: 75 mg/kg IM, IV q 8 h. Neonate > 1 wk and < 2 kg: 75 mg/kg IM, IV q 8 h. Neonate > 1 wk and > 2 kg: 100 mg/kg IM, IV q 8 h. Infant, child > 1 month and < 40 kg: 200-300 mg/kg IV qd in divided doses q 4-6 h. Child = 40 kg, adult: 200-300 mg/kg IV qd in divided doses q 3, 4, or 6 h.
UTI- Infant, child > 1 month and < 40 kg: Complicated infection: 150-200 mg/kg IV qd in divided doses q 4-6 h. Uncomplicated infection: 50-100 mg/kg IV, IM qd in divided doses q 6-8 h. Total qd dose in child shouldnt exceed adult dose. Child = 40 kg, adult: Complicated infection:150-200 mg/kg IV qd in divided doses q 4-6 h. Uncomplicated infection: 1 gram IV, IM q 6 h. |